Sunday, September 27, 2009

What is Zentel?

What do u know about Zentel? Is it a name of society? or a cafe? Actually is a name of medicine.
Below are the information about Zentel.

Propreitary names :
ZENTEL® TABLETS 200 mg (tablets)
ZENTEL® SUSPENSION 20 mg/mL (suspension)

COMPOSITION:
The chemical name of albendazole is methyl [5-(propylthio)-1H-benzimidazol-2-yl] carbamate.
Each ZENTEL 200 mg tablet contains 200 mg
albendazole.
The suspension contains 100 mg albendazole in each 5 mL, preserved with potassium sorbate 0,39% m/v, benzoic acid 0,2% m/v and sorbic acid 0,08% m/v.

What is 'albendazole' ?
Albendazole, marketed as Albenza, Eskazole and Zentel, is a member of teh benzimidazole coumpounds used as a drug indicated for the treatment of varitey of worm infestations.

sides effects:

Albendazole may cause dizziness, headache, fever, nausea, vomiting, or temporary hair loss.In rare cases it may cause persistent sore throat, severe headache, seizures, vision problems, yellowing eyes or skin, dark urine, stomach pain, easy bruising, mental/mood changes, very stiff neck, change in amount of urine. Allergic reactions are also possible. (wikipedia)

INDICATIONS:
ZENTEL is indicated in the treatment of single or mixed intestinal parasites. Clinical studies have shown albeneffective in the treatment of Ascaris lumbricoides (roundworm), Trichuris trichiura (whipworm), Enterobius vermicularis (pinworm/threadworm), Ancylostoma duodenale and Necator americanus (hookworm), Taenia spp. (tapeworm) and Strongyloides stercoralis.
ZENTEL has been shown to be effective in the treatment of Giardia (duodenalis or intestinalis or lamblia) infections in children.

CONTRA-INDICATIONS:
Albendazole is known to be teratogenic and embryotoxic in animals. The safety of albendazole during pregnancy has not been established, and ZENTEL should not be taken by pregnant women at any stage of their pregnancy or by women who are likely to become pregnant, during or shortly after the course of therapy. ZENTEL is contra-indicated in patients with a known history of hypersensitivity to albendazole or constituents.

OSAGE AND DIRECTIONS FOR USE:
Usual Dose:
400 mg (two ZENTEL 200 mg tablets) or 20 mL (400 mg) of ZENTEL suspension as a single dose in both adults and children over two years of age. The tablets may be chewed, swallowed or crushed and mixed with food. The usual dose in children between one and two years of age is 10 mL (200 mg) of ZENTEL suspension as a single dose. In heavy mixed infestation involving Strongyloides or Taeniasis, a single daily dose may be inadequate and the dose may be given for three consecutive days.

SIDE-EFFECTS AND SPECIAL PRECAUTIONS:
Gastrointestinal discomfort, diarrhoea, headache and dizziness have been reported.
Hypersensitivity reactions including rash. pruritus and urticaria have been reported less frequently.
Interactions:
Praziquantel has been reported to increase the plasma levels of the albendazole active metabolite.

KNOWN SYMPTOMS OF OVERDOSAGE AND PARTICULARS OF ITS TREATMENT:
If poisoning or excessive overdosage is suspected it is recommended, on general principles, that vomiting be induced or gastric lavage be performed, and such symptomatic supportive therapy be administered as appears indicated.

soucers:
http://home.intekom.com/pharm/smith_kb/zentel.html

6 comments:

Unknown said...

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Unknown said...
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